Carbamimidoyl-nitroso-acetic acid ethyl ester → HCID 12439913, 화합물
반응식
[CH2:1]([O:3][C:4](=[O:11])[CH:5]([C:8](=[NH:10])[NH2:9])[N:6]=O)[CH3:2]>C(O)C.[Pd]>[CH2:1]([O:3][C:4](=[O:11])[CH:5]([NH2:6])[C:8](=[NH:9])[NH2:10])[CH3:2]참가 물질
4
실험 절차
To a solution of carbamimidoyl-nitroso-acetic acid ethyl ester (5.5 g, 31.4 mmol) in ethanol/5M HCl (1:1 ratio, 250 ml) was added 10% Pd/C (1.3 g). The reaction mixture was hydrogenated (H2(g)) at low pressure over 2 nights. The Pd/C was filtered through Celite® (filter material) and the filtrate reduced in vacuo to give the title compound as a white solid. This was taken through to the next step as crude.
후처리
- customover 2 nights
- filtrationThe Pd/C was filtered through Celite® (filter material)
출처 및 근거
- ORD 기록
- ord-1364371600aa48d8973427e77a526ee5
- 출처 데이터셋
- uspto-grants-2013_07
- 특허 번호
- US08476269B2
반응 노트
불러오는 중…