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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 444938생성일: 2026년 10월 25일

(4-Chloro-2-methylphenyl)boronic acid → 3-Amino-6-(4-chloro-2-methyl-phenyl)-5-trifluoromethyl-pyridine-2-carboxylic acid

https://huagongshe.com/reaction/444938

반응식

참여 물질

역할이름HCID투입량
반응물(4-Chloro-2-methylphenyl)boronic acidHCID 5017600—
반응물Methyl 3-amino-6-bromo-5-(trifluoromethyl)picolinateHCID 58964428—
생성물3-Amino-6-(4-chloro-2-methyl-phenyl)-5-trifluoromethyl-pyridine-2-carboxylic acidHCID 68169540—

반응 단계

This compound was prepared from 3-Amino-6-bromo-5-trifluoromethyl-pyridine-2-carboxylic acid methyl ester (Intermediate A4) and 4-chloro-2-methylphenylboronic acid analogously to Intermediate H; LC-MS Rt=1.53 mins, [M+H]+ 331 (Method 2 min LC_v002).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08476269B2
출처 데이터셋uspto-grants-2013_07
ORD IDord-6e675906c96b4adb9caa95d8fc401b9b
출처 메모uspto-grants-2013_07