2-Azabicyclo[2.2.1]heptan-4-amine, N-1H-indazol-5-yl- → N-(5-((-4-((1H-indazol-5-yl)amino)-2-azabicyclo[2.2.1]heptan-2-yl)methyl)-2-methylphenyl)methanesulfonamide

HRID 445132노트

반응식

HRID 445132 반응식
[CH:1]12[CH2:7][C:4]([NH:8][C:9]3[CH:10]=[C:11]4[C:15](=[CH:16][CH:17]=3)[NH:14][N:13]=[CH:12]4)([CH2:5][CH2:6]1)[CH2:3][NH:2]2.[CH:18]([C:20]1[CH:21]=[CH:22][C:23]([CH3:31])=[C:24]([NH:26][S:27]([CH3:30])(=[O:29])=[O:28])[CH:25]=1)=O>>[NH:14]1[C:15]2[C:11](=[CH:10][C:9]([NH:8][C:4]34[CH2:7][CH:1]([CH2:6][CH2:5]3)[N:2]([CH2:18][C:20]3[CH:21]=[CH:22][C:23]([CH3:31])=[C:24]([NH:26][S:27]([CH3:30])(=[O:29])=[O:28])[CH:25]=3)[CH2:3]4)=[CH:17][CH:16]=2)[CH:12]=[N:13]1

참가 물질

3

반응물 2

HCID 672342982-Azabicyclo[2.2.1]heptan-4-amine, N-1H-indazol-5-yl-HCID 86654427HCID 86654427, 화합물

생성물 1

HCID 53247675N-(5-((-4-((1H-indazol-5-yl)amino)-2-azabicyclo[2.2.1]heptan-2-yl)methyl)-2-methylphenyl)methanesulfonamide

실험 절차

Reaction of Intermediate 25 with N-(5-formyl-2-methylphenyl)methanesulfonamide affords the title compound.

출처 및 근거

ORD 기록
ord-41c716b4053245e9b7957c2c68a018dd
출처 데이터셋
uspto-grants-2013_07
특허 번호
US08476295B2

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