Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethanol → 2-(5-Bromo-pyridin-3-yl)-N-methyl-acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethanol | HCID 702 | — |
| 반응물 | Methylamine | HCID 6329 | — |
| 반응물 | 2-(5-Bromopyridin-3-yl)acetic acid | HCID 2802539 | — |
| 생성물 | 2-(5-Bromo-pyridin-3-yl)-N-methyl-acetamide | HCID 54236812 | — |
반응 단계
The title compound was synthesized in a similar manner as described for Example 103 using (5-bromo-pyridin-3-yl)-acetic acid (ABCR, Karlsruhe, Germany, 1.815 mmol) and 8 M methylamine in EtOH (Aldrich, Buchs, Switzerland, 7.26 mmol) to give the title compound as an off-white solid. (HPLC: tR 1.74 min (Method A); M+H=229, 231 MS-ES)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08476294B2 |
| 출처 데이터셋 | uspto-grants-2013_07 |
| ORD ID | ord-2a07b27fc62142d5a8c6f5ad95515fb3 |
| 출처 메모 | uspto-grants-2013_07 |