Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diethyl Ether → N'-(1-acetylpiperidin-4-ylidene)benzohydrazide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diethyl Ether | HCID 3283 | — |
| 반응물 | Benzoylhydrazine | HCID 11955 | — |
| 반응물 | N-Acetyl-4-piperidone | HCID 122563 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | N'-(1-acetylpiperidin-4-ylidene)benzohydrazide | HCID 57531701 | 83% |
반응 단계
20 g (0.142 mol) of 1-acetyl-4-piperidone were dissolved in 400 mL of absolute ethanol and 21.2 g (0.156 mol) of benzoylhydrazine were added. The resulting solution was refluxed for 6 hours under stirring. The solvent was then removed in vacuo and the residue partitioned between dichloromethane and water. The organic layer was dried over sodium sulfate and evaporated to dryness. The residue was triturated with diethylether and 30 g (83% yield) of the title compound were collected by filtration.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08541429B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-d168168c723d46c08635a1699a165a5d |
| 출처 메모 | uspto-grants-2013_09 |