Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → (1S)-1-methyl-2-morpholin-4-yl-2-oxo-1-phenylethylamine hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | tert-butoxycarbonyl-(1S)-1-methyl-2-morpholin-4-yl-2-oxo-1-phenylethylamine | HCID 57444165 | — |
| 용매 | 1,4-Dioxane | HCID 31275 | — |
| 생성물 | (1S)-1-methyl-2-morpholin-4-yl-2-oxo-1-phenylethylamine hydrochloride | HCID 57444166 | — |
반응 단계
A solution of 630 mg (1.884 mmol) of N-(tert-butoxycarbonyl)-(1S)-1-methyl-2-morpholin-4-yl-2-oxo-1-phenylethylamine in 20 mL of dioxane was treated with 2.5 mL of HCl 4N in dioxane overnight. The solvent was removed under vacuo and the solid was triturated with diethylether yielding 560 mg of the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08541429B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-015e1834be00428fb7598a2baa2a1816 |
| 출처 메모 | uspto-grants-2013_09 |