7-Benzoyl-2-oxindole → 7-Acetyloxindole

HRID 4477노트

반응식

HRID 4477 반응식
[C:1]([C:5]1[CH:6]=[CH:7][CH:8]=[C:9]2[C:13]=1[NH:12][C:11](=[O:14])[CH2:10]2)(=[O:4])[CH2:2]C.C(C1C=CC=C2C=1NC(=O)C2)(=O)C1C=CC=CC=1.C1(C(C2C=CC=C3C=2NC(=O)C3)=O)SC=CC=1.C1SC=CC=1C(C1C=CC=C2C=1NC(=O)C2)=O.CC1C=C2C(=C(C(=O)C)C=1)NC(=O)C2.CSC1C=C2C(=C(C(=O)C)C=1)NC(=O)C2.FC1C=C2C(=C(C(=O)C3C=CC=CC=3)C=1)NC(=O)C2.BrC1C=C2C(=C(C(=O)C3SC=CC=3)C=1)NC(=O)C2>>[C:1]([C:5]1[CH:6]=[CH:7][CH:8]=[C:9]2[C:13]=1[NH:12][C:11](=[O:14])[CH2:10]2)(=[O:4])[CH3:2]

참가 물질

9

반응물 8

HCID 1709837-Benzoyl-2-oxindoleHCID 13408141HCID 13408141, 화합물HCID 21282036HCID 21282036, 화합물HCID 21282054HCID 21282054, 화합물HCID 212820565-Bromo-7-(2-thenoyl)oxindoleHCID 21282068HCID 21282068, 화합물HCID 212820915-Methylthio-7-acetyloxindoleHCID 54218701HCID 54218701, 화합물

생성물 1

HCID 137705297-Acetyloxindole

실험 절차

Starting with the appropriate reagents and following the procedure of Preparation K, 7-propionyloxindole, 7-benzoyloxindole, 7-(2-thenoyl)oxindole, 7-(3-thenoyl)oxindole, 5-methyl-7-acetyloxindole, 5-methylthio-7-acetyloxindole, 5-fluoro-7-benzoyloxindole and 5-bromo-7-(2-thenoyl)oxindole are prepared.

후처리

  1. customare prepared

출처 및 근거

ORD 기록
ord-62114cd74ab5480d93d8211eeeebf13b
출처 데이터셋
uspto-grants-1988_02
특허 번호
US04725616

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