6,7-Methylenedioxyoxindole → 5H-[1,3]dioxolo[4,5-f]indole

HRID 4479노트

반응식

HRID 4479 반응식
[CH2:1]1[O:12][C:11]2[CH:10]=[C:9]3[C:5]([CH2:6][C:7](=O)[NH:8]3)=[CH:4][C:3]=2[O:2]1.[N+](C1C=C2OCOC2=CC=1CC(OC)=O)([O-])=O.[N+](C1OC2C(=C(CC(OC)=O)C=CC=2)O1)([O-])=O.C1OC2C(=C3C(=CC=2)NC(=O)C3)O1.C1OC2C(=CC=C3C=2NC(=O)C3)O1>>[CH2:1]1[O:12][C:11]2[CH:10]=[C:9]3[C:5]([CH:6]=[CH:7][NH:8]3)=[CH:4][C:3]=2[O:2]1

참가 물질

6

반응물 5

HCID 212820116,7-MethylenedioxyoxindoleHCID 212820234,5-MethylenedioxyoxindoleHCID 212821015,6-MethylenedioxyoxindoleHCID 21282102Methyl 2-(6-nitrobenzo[d][1,3]dioxol-5-yl)acetateHCID 70406732Methyl 2-nitromethylenedioxyphenylacetate

생성물 1

HCID 2607975H-[1,3]dioxolo[4,5-f]indole

실험 절차

5,6-Methylenedioxyoxindole can be prepared via the reduction of methyl 2-nitro-4,5-methylenedioxyphenylacetate according to the procedure of McEvoy et al., J. Org. Chem., 38, 3350 (1973). By a similar procedure, starting with the appropriate methyl 2-nitromethylenedioxyphenylacetate, 4,5-methylenedioxyoxindole and 6,7-methylenedioxyoxindole are prepared.

후처리

  1. customare prepared

출처 및 근거

ORD 기록
ord-3ed5c8b0016f4432bfed93da605fb3ce
출처 데이터셋
uspto-grants-1988_02
특허 번호
US04725616

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