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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 44804생성일: 2026년 10월 25일

(R)-Methyl 2-((2-chloro-5-nitropyrimidin-4-yl)(cyclopentyl)amino)butanoate → (R)-methyl 2-((2-chloro-5-nitropyrimidin-4-yl)(isopropyl)amino)butanoate

https://huagongshe.com/reaction/44804

반응식

참여 물질

역할이름HCID투입량
반응물(R)-Methyl 2-((2-chloro-5-nitropyrimidin-4-yl)(cyclopentyl)amino)butanoateHCID 58405447—
용매AcetoneHCID 180—
생성물(R)-methyl 2-((2-chloro-5-nitropyrimidin-4-yl)(isopropyl)amino)butanoateHCID 59815009—

반응 단계

Intermediate C-1 was prepared similarly to the synthetic methods used to prepare Intermediate A with the exception that acetone was used instead of cyclopentanone in the reductive amination step.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08541418B2
출처 데이터셋uspto-grants-2013_09
ORD IDord-3fd893af0d6544c4821cd0d1f8d7b325
출처 메모uspto-grants-2013_09