HCID 519042, 화합물 → 1-(2-methylthiazol-5-yl)ethanone
반응식
Br[C:2](=[C:6]([OH:8])[CH3:7])[C:3](=O)C.[C:9]([NH2:12])(=[S:11])[CH3:10]>CC(C)=O>[C:6]([C:2]1[S:11][C:9]([CH3:10])=[N:12][CH:3]=1)(=[O:8])[CH3:7]참가 물질
4
실험 절차
To a solution of the product of Example 151B (14.5 g, 88 mmol) in acetone (220 mL) was added thioacetamide (6.6 g, 88 mmol) and stirred overnight. The solid was filtered to give the title compound as the hydrogen bromide salt. 1H NMR (300 MHz, DMSO-d6) δ ppm 2.54 (s, 3 H) 2.71 (s, 3 H) 8.46 (s, 1 H). MS (DCI) m/z 142 (M+H)+.
후처리
- filtrationThe solid was filtered
출처 및 근거
- ORD 기록
- ord-7ce2d9ad574a4beea8cdfbe631fa4f0f
- 출처 데이터셋
- uspto-grants-2013_07
- 특허 번호
- US08481574B2
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