Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,3-Dichloro-5,6-dicyano-1,4-benzoquinone → 6-Bromo-1,10-dihydropyrrolo[2,3-a]carbazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone | HCID 6775 | — |
| 반응물 | 3-Bromophenylhydrazine hydrochloride | HCID 33757 | — |
| 반응물 | Sodium Acetate | HCID 517045 | — |
| 반응물 | Cyclohexane ethylacetate | HCID 21867204 | — |
| 생성물 | 6-Bromo-1,10-dihydropyrrolo[2,3-a]carbazole | HCID 58488489 | 45% |
반응 단계
3-bromophenylhydrazine hydrochloride (1.00 g; 4.47 mmol), sodium acetate (367 mg; 4.47 mmol); stage B: DDQ (454 mg; 2.00 mmol); stage C: chromatography on silica gel (9/1 and then 8/2 cyclohexane/EtOAc) allows isolation of the compound of Example 25 (513 mg; 1.80 mmol; yield=45%) and the compound of Example 26 (342 mg; 1.20 mmol; yield=30%) in the form of gray solids.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08481586B2 |
| 출처 데이터셋 | uspto-grants-2013_07 |
| ORD ID | ord-021048a1da3c4865b356017749a3eb7e |
| 출처 메모 | uspto-grants-2013_07 |