Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Isoquinoline → isoquinolin-N-oxide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Isoquinoline | HCID 8405 | — |
| 반응물 | m-Chloroperbenzoic acid | HCID 70297 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | isoquinolin-N-oxide | HCID 290378 | — |
반응 단계
To a stirred solution of isoquinoline (1-Im-9, 5 g, 1.0 eq) in 50 mL of CHCl3, mCPBA (2.0 eq) was added. The mixture was stirred at rt for 1 h. The reaction was washed with 5% aqueous Na2SO3 and aqueous Na2CO3, then concentrated and the residue was purified by silica column chromatography to give isoquinoline 2-oxide (2-Im-9).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08541418B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-e6b18eeb6a8c4466b0200d7320f148d3 |
| 출처 메모 | uspto-grants-2013_09 |