Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phosgene → 2-(1-Methoxycarbonylethoxy)benzenesulfonyl isocyanate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phosgene | HCID 6371 | — |
| 반응물 | Butyl isocyanate | HCID 8110 | — |
| 반응물 | 2-(1-Methoxycarbonylethoxy)benzenesulfonamide | HCID 22152837 | — |
| 촉매 | Diazabicyclooctane | HCID 66583054 | — |
| 용매 | O-Xylene | HCID 7237 | — |
| 생성물 | 2-(1-Methoxycarbonylethoxy)benzenesulfonyl isocyanate | HCID 22152836 | 125.5% |
반응 단계
A mixture of 12.9 g of 2-(1-methoxycarbonylethoxy)-benzenesulfonamide, 4.9 g of n-butylisocyanate and 0.1 g of diazabicyclooctane and 130 ml of xylene is refluxed for 30 minutes. Then 10 g of phosgene are passed into the solution at the same temperature over 90 minutes. Excess phosgene is expelled with nitrogen and the solution is then cooled and concentrated in vacuo, affording 17.7 g of 2-(1-methoxycarbonylethoxy)benzenesulfonyl isocyanate in the form of a brownish oil which can be further used without purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04726836 |
| 출처 데이터셋 | uspto-grants-1988_02 |
| ORD ID | ord-256cd9153e88410d975da315b2913afe |
| 출처 메모 | uspto-grants-1988_02 |