Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 2,4-dichloro-N-(1-methyltetrazol-5-yl)benzamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Pyridine | HCID 1049 | — |
| 반응물 | 2,4-Dichlorobenzoyl chloride | HCID 66645 | — |
| 반응물 | 1-methyl-1H-tetrazol-5-amine | HCID 138492 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | 2,4-dichloro-N-(1-methyltetrazol-5-yl)benzamide | HCID 66606525 | — |
반응 단계
In a microwave oven, 209 mg (1.0 mmol) of 2,4-dichlorobenzoyl chloride, 198 mg (2.0 mmol) of 1-methyl-5-aminotetrazole and 237 mg (3 mmol) of pyridine in 3 ml of acetonitrile are stirred at 130° C. for 45 min. Water is then added, and the product is filtered off with suction and washed with ether. Yield 80 mg (30%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08481749B2 |
| 출처 데이터셋 | uspto-grants-2013_07 |
| ORD ID | ord-1e077ed3306f4005a44ab0d8c8cd395b |
| 출처 메모 | uspto-grants-2013_07 |