2-chloro-1H-imidazole → HCID 58405414, 화합물

HRID 44890노트

반응식

HRID 44890 반응식
Cl[C:2]1[N:11]=[CH:10][C:9]2[N:8]([CH3:12])[C:7](=[O:13])[C@@H:6]([CH2:14][CH3:15])[N:5]([CH:16]3[CH2:20][CH2:19][CH2:18][CH2:17]3)[C:4]=2[N:3]=1.[Cl:21][C:22]1[NH:23][CH:24]=[CH:25][N:26]=1>>[Cl:21][C:22]1[N:23]([C:2]2[N:11]=[CH:10][C:9]3[N:8]([CH3:12])[C:7](=[O:13])[C@@H:6]([CH2:14][CH3:15])[N:5]([CH:16]4[CH2:20][CH2:19][CH2:18][CH2:17]4)[C:4]=3[N:3]=2)[CH:24]=[CH:25][N:26]=1

참가 물질

3

반응물 2

HCID 27733282-chloro-1H-imidazoleHCID 24820413(R)-2-Chloro-8-cyclopentyl-7-ethyl-5-methyl-7,8-dihydropteridin-6(5H)-one

생성물 1

HCID 58405414HCID 58405414, 화합물

실험 절차

The title compound was prepared similarly to the methods described in Example 185, with Intermediate B instead of Intermediate C and 2-chloro-1H-imidazole instead of 2-(3,5-dichlorophenyl)-1H-imidazole. LCMS: 361.2 m/z (M+H)+; ret. Time 10.06 min (Analytical Method C).

출처 및 근거

ORD 기록
ord-e71c86cd3cf9420387d3275af668b893
출처 데이터셋
uspto-grants-2013_09
특허 번호
US08541418B2

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