3-[(4-Methylamino-3-nitro-benzoyl)-phenyl-amino]propionic acid methyl ester → 3-[(3-Amino-4-methylamino-benzoyl)-phenyl-amino]propionic acid methyl ester
반응식
[CH3:1][O:2][C:3](=[O:26])[CH2:4][CH2:5][N:6]([C:13](=[O:25])[C:14]1[CH:19]=[CH:18][C:17]([NH:20][CH3:21])=[C:16]([N+:22]([O-])=O)[CH:15]=1)[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1>C(O)C.[Pd]>[CH3:1][O:2][C:3](=[O:26])[CH2:4][CH2:5][N:6]([C:13](=[O:25])[C:14]1[CH:19]=[CH:18][C:17]([NH:20][CH3:21])=[C:16]([NH2:22])[CH:15]=1)[C:7]1[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=1참가 물질
4
실험 절차
The nitro group of product 1a was reduced by hydrogenation at room temperature in ethanol with Pd (10% on charcoal) as catalyst.
출처 및 근거
- ORD 기록
- ord-b68e988376204a00b19fe2b828d3edf2
- 출처 데이터셋
- uspto-grants-2013_07
- 특허 번호
- US08486398B2
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