Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethylamine → HCID 67128887, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethylamine | HCID 674 | — |
| 반응물 | Benzenedicarboxylic acid, dichloro- | HCID 39047 | — |
| 반응물 | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| 용매 | Dichloromenthane | HCID 21946423 | — |
| 생성물 | HCID 67128887 | HCID 67128887 | — |
반응 단계
To a solution of 2,6-dichloroterephthalic acid (100 mg, 0.46 mmol) in dichloromenthane was added CDI (62 mg, 0.46 mmol) in one portion. The reaction mixture was stirred at room temperature for 1.5 hours and then dimethyl amine (1.0 M in THF, 2 mL, 2.0 mmol) was added. The reaction was concentrated under reduced pressure to give the crude 2,6-dichloro-4-(dimethylcarbamoyl)benzoic acid, which was used in the next step without further purification. 1H NMR (500 MHz, DMSO-d6): δ 14.35 (s, 1H), 7.56 (s, 2H), 2.97 (s, 3H), 2.89 (s, 3H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08486950B2 |
| 출처 데이터셋 | uspto-grants-2013_07 |
| ORD ID | ord-763c3c867a3e45b58807a5388d5794a5 |
| 출처 메모 | uspto-grants-2013_07 |