4-Aminobenzoic Acid → Benzoyl chloride, 4-amino-

HRID 450032

반응식

HRID 450032 반응식
[NH2:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](O)=[O:7])=[CH:4][CH:3]=1.S(Cl)([Cl:13])=O>>[NH2:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([Cl:13])=[O:7])=[CH:4][CH:3]=1

참가 물질

3

반응물 2

HCID 9784-Aminobenzoic AcidHCID 24386Thionyl Chloride

생성물 1

HCID 177720Benzoyl chloride, 4-amino-수율 100%

실험 절차

Thionyl chloride (10 ml) was added to 4-aminobenzoic acid (1.0 g, 7.29 mmol) and the solution was heated to reflux for 16 hr. Thionyl chloride was removed under vacuum to yield 4-amino-benzoyl chloride (1.13 g, 100%).

후처리

  1. temperaturethe solution was heated
  2. temperatureto reflux for 16 hr
  3. customThionyl chloride was removed under vacuum

출처 및 근거

ORD 기록
ord-9d3164fac3724e69be08b9297f716ecf
출처 데이터셋
uspto-grants-2013_07
특허 번호
US08486962B2

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