Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1H-Pyrazol-3-amine, 5-methyl- → 2-Chloro-6-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-5-nitropyrimidin-4-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1H-Pyrazol-3-amine, 5-methyl- | HCID 93146 | — |
| 반응물 | 2,4,6-Trichloro-5-nitropyrimidine | HCID 4297843 | — |
| 반응물 | Sodium Methoxide | HCID 10942334 | — |
| 생성물 | 2-Chloro-6-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-5-nitropyrimidin-4-amine | HCID 86649285 | — |
반응 단계
The title compound was prepared using a procedure similar to the one described for the synthesis of Intermediate 18 using 2,4,6-trichloro-5-nitropyrimidine (Intermediate 37), 5-methyl-1H-pyrazol-3-amine and sodium methoxide as the starting materials. LCMS: 285 [M+1].
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08486966B2 |
| 출처 데이터셋 | uspto-grants-2013_07 |
| ORD ID | ord-142abff36d424c32981f1d185e0f9f1c |
| 출처 메모 | uspto-grants-2013_07 |