Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ammonia → 5-(5-Bromopyridin-3-yl)-3-(pyridin-3-yl)-1,2,4-oxadiazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ammonia | HCID 222 | — |
| 반응물 | N-Hydroxynicotinimidamide | HCID 308113 | — |
| 반응물 | 5-Bromonicotinoyl chloride | HCID 2781223 | — |
| 생성물 | 5-(5-Bromopyridin-3-yl)-3-(pyridin-3-yl)-1,2,4-oxadiazole | HCID 59758751 | — |
반응 단계
The title compound was prepared according to the procedure of Example 1 using N′-hydroxynicotinimidamide (Aldrich) and 5-bromonicotinoyl chloride (Alfa). 1H NMR (300 MHz, DMSO-d6) δ 8.65-8.69 (m, 1 H), 8.45-8.49 (m, 1 H), 8.79 (t, J=1.7 Hz, 1 H), 8.84 (dd, J=1.7, 2.0 Hz, 1 H), 9.07 (d, J=2 Hz, 1 H), 9.28-9.29 (m, 1 H), 9.34 (d, J=1.7 Hz, 1 H) ppm; MS (DCI/NH3) m/z 303 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08486979B2 |
| 출처 데이터셋 | uspto-grants-2013_07 |
| ORD ID | ord-fffafc31a37c478bb4cb5d9a6babb961 |
| 출처 메모 | uspto-grants-2013_07 |