Oxalyl chloride → HCID 59819913, 화합물

HRID 450595노트

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HRID 450595 반응식
[F:1][C:2]([F:16])([F:15])[S:3]([C:6]1[CH:7]=[C:8]([CH:12]=[CH:13][CH:14]=1)[C:9](O)=[O:10])(=[O:5])=[O:4].C(Cl)(=O)C([Cl:20])=O>ClCCl.CN(C)C=O>[F:1][C:2]([F:16])([F:15])[S:3]([C:6]1[CH:7]=[C:8]([CH:12]=[CH:13][CH:14]=1)[C:9]([Cl:20])=[O:10])(=[O:5])=[O:4]

참가 물질

5

반응물 2

HCID 65578Oxalyl chlorideHCID 155846983-(Trifluoromethylsulphonyl)benzoic acid

생성물 1

HCID 59819913HCID 59819913, 화합물

시약·촉매·용매 2

HCID 6228Dimethylformamide촉매HCID 6344Dichloromethane용매

실험 절차

A solution of the product of Example 6A (198 mg, 0.8 mmol) in dichloromethane (10 mL) was stirred with oxalyl dichloride (Aldrich, 2.0 mmol) and 1 drop of dimethylformamide at ambient temperature for 2 hours. The title compound was obtained by removing the solvent under vacuum as a yellow oil (250 mg) and the compound was used directly in the next step.

출처 및 근거

ORD 기록
ord-b6b6275bbfcb43ffa6af08cb1a88f9bb
출처 데이터셋
uspto-grants-2013_07
특허 번호
US08486979B2

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