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[OH:1][N:2]=[C:3]([NH2:10])[C:4]1[CH:9]=[CH:8][CH:7]=[N:6][CH:5]=1.[F:11][C:12]1[C:20]([F:21])=[CH:19][CH:18]=[CH:17][C:13]=1[C:14](O)=O.N>>[F:11][C:12]1[C:20]([F:21])=[CH:19][CH:18]=[CH:17][C:13]=1[C:14]1[O:1][N:2]=[C:3]([C:4]2[CH:5]=[N:6][CH:7]=[CH:8][CH:9]=2)[N:10]=1참가 물질
4
실험 절차
The title compound was prepared according to the procedure of Example 8 using N′-hydroxynicotinimidamide (Aldrich) and 2,3-difluorobenzoic acid (Aldrich). 1H NMR (300 MHz, CD3OD) δ 7.51-7.67 (m, 2 H), 8.08-8.14 (m, 1 H), 8.18 (ddd, J=10.7, 7.5, 2.0 Hz, 1 H), 8.55 (dt, J=8.0, 1.9 Hz, 1 H), 8.74 (dd, J=5.2, 1.6 Hz, 1 H), 9.29 (dd, J=2.4, 0.8 Hz, 1 H) ppm; MS (DCI/NH3) m/z 260 (M+H)+.
출처 및 근거
- ORD 기록
- ord-68a6967accc84f688344c7ee091e3fc7
- 출처 데이터셋
- uspto-grants-2013_07
- 특허 번호
- US08486979B2
연결된 노트
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