Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ammonia → 5-(Pyrazin-2-yl)-3-(pyridin-3-yl)-1,2,4-oxadiazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ammonia | HCID 222 | — |
| 반응물 | 2-Pyrazinecarboxylic acid | HCID 1047 | — |
| 반응물 | N-Hydroxynicotinimidamide | HCID 308113 | — |
| 생성물 | 5-(Pyrazin-2-yl)-3-(pyridin-3-yl)-1,2,4-oxadiazole | HCID 16418461 | — |
반응 단계
The titled compound was prepared according to the procedure of Example 8 using N′-hydroxynicotinimidamide (Aldrich) and pyrazine-2-carboxylic acid (Aldrich). 1H NMR (300 MHz, CD3OD) δ 7.66 (ddd, J=8.0, 4.9, 1.0 Hz, 1 H), 8.60 (dt, J=8.0, 1.9 Hz, 1 H), 8.77 (dd, J=5.0, 1.8 Hz, 1 H), 8.86-8.89 (m, 1 H), 8.89-8.91 (m, 1 H), 9.34 (dd, J=2.4, 0.8 Hz, 1H), 9.56 (d, J=1.6 Hz, 1 H) ppm; MS (DCI/NH3) m/z 226 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08486979B2 |
| 출처 데이터셋 | uspto-grants-2013_07 |
| ORD ID | ord-8ae5f3fd252a419398ad3fed739ace43 |
| 출처 메모 | uspto-grants-2013_07 |