Ammonia → HCID 44544869, 화합물

반응식

[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([C:10]([OH:12])=O)[CH:8]=2)[CH:3]=[CH:2]1.O[N:14]=[C:15]([NH2:22])[C:16]1[CH:21]=[CH:20][CH:19]=[N:18][CH:17]=1.N>>[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([C:10]3[O:12][N:22]=[C:15]([C:16]4[CH:17]=[N:18][CH:19]=[CH:20][CH:21]=4)[N:14]=3)[CH:8]=2)[CH:3]=[CH:2]1

참가 물질

반응물 3

HCID 222Ammonia

HCID 308113N-Hydroxynicotinimidamide

HCID 5952301H-indole-6-carboxylic acid

생성물 1

HCID 44544869HCID 44544869, 화합물

실험 절차

The title compound was prepared according to Method C using 1H-indole-6-carboxylic acid (Aldrich) and N′-hydroxynicotinimidamide (Tyger). 1H NMR (300 MHz, DMSO-d6) δ 6.62 (ddd, J=3.0, 1.9, 0.8 Hz, 1 H), 7.62-7.71 (m, 2 H), 7.76-7.89 (m, 2 H), 8.27-8.33 (m, J=1.4 Hz, 1 H), 8.46 (dt, J=8.2, 1.9, 1.7 Hz, 1 H), 8.82 (dd, J=4.7, 1.7 Hz, 1 H), 9.27 (dd, J=2.2, 0.8 Hz, 1 H), 11.66 (s, 1 H) ppm; MS (DCI/NH3) m/z 263 (M+H)+.

출처 및 근거

ORD 기록: ord-3bb1515410a143d49331c5aabd9ad903
출처 데이터셋: uspto-grants-2013_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08486979B2

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