Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-[6-(Hydroxymethyl)pyridin-2-yl]ethanone oxime → [6-(1-Aminoethyl)pyridin-2-yl]methanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-[6-(Hydroxymethyl)pyridin-2-yl]ethanone oxime | HCID 136346367 | — |
| 촉매 | HCID 178418390 | HCID 178418390 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | [6-(1-Aminoethyl)pyridin-2-yl]methanol | HCID 55295264 | 91% |
반응 단계
To a solution of 1.8 g of 1-[6-(hydroxymethyl)pyridin-2-yl]ethanone oxime in 36 ml of methanol was added 500 mg of 10% palladium-carbon (50% wet) under an argon atmosphere, followed by stifling for 7 hours under a hydrogen atmosphere. After filtration through Celite, the filtrate was evaporated under reduced pressure to obtain 1.5 g of [6-(1-aminoethyl)pyridin-2-yl]methanol.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08486970B2 |
| 출처 데이터셋 | uspto-grants-2013_07 |
| ORD ID | ord-3ea457aa8eff462997f1b944d7f8ae7f |
| 출처 메모 | uspto-grants-2013_07 |