Pyridinium chloride → 2-i-Propyl-5-(2-thiophene-2-ylethenyl)-1,3-benzenediol

HRID 450909노트

반응식

HRID 450909 반응식
C[O:2][C:3]1[CH:4]=[C:5]([CH:14]=[CH:15][C:16]2[S:17][CH:18]=[CH:19][CH:20]=2)[CH:6]=[C:7]([O:12]C)[C:8]=1[CH:9]([CH3:11])[CH3:10].Cl.N1C=CC=CC=1>>[CH:9]([C:8]1[C:3]([OH:2])=[CH:4][C:5]([CH:14]=[CH:15][C:16]2[S:17][CH:18]=[CH:19][CH:20]=2)=[CH:6][C:7]=1[OH:12])([CH3:11])[CH3:10]

참가 물질

3

반응물 2

HCID 10176127Pyridinium chlorideHCID 68798830HCID 68798830, 화합물

생성물 1

HCID 687987972-i-Propyl-5-(2-thiophene-2-ylethenyl)-1,3-benzenediol수율 24%

실험 절차

This material was prepared from 2-[2-(3.5-dimethoxy-4-i-propylphenyl)ethenyl]thiophene obtained in example 17 and pyridine hydrochloride in 24% yield as the same way as described in example 2(b). 1HNMR (CDCl3, ppm): δ 1.40 (d, J=7.1 Hz), 3.47 (qint., J=7.1 Hz, 1H), 4.8 (b, 2H), 6.48 (s, 2H), 6.74 (d, J=16Hz, 1H), 7.0-7.1 (m, 3H), 7.2-7.3 (m, 1H).

출처 및 근거

ORD 기록
ord-86191decc13f41d9ab873f2cb21c92bb
출처 데이터셋
uspto-grants-2013_07
특허 번호
US08487009B2

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