Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Heptyne → 1-(4-Hept-1-ynyl-3-methoxy-phenyl)ethanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Heptyne | HCID 12350 | — |
| 반응물 | Toluene-4-sulfonic acid 4-acetyl-2-methoxy-phenyl ester | HCID 29800848 | — |
| 용매 | Dichloromethane heptane | HCID 21907733 | — |
| 생성물 | 1-(4-Hept-1-ynyl-3-methoxy-phenyl)ethanone | HCID 25221497 | — |
반응 단계
This product was prepared from toluene-4-sulfonic acid 4-acetyl-2-methoxy-phenyl ester and 1-heptyne following the general procedure for the Sonogashira cross-coupling process described above. Chromatography eluent: heptane/DCM 1:1; yield (110 mg, 90%); 1H NMR δ (CDCl3): 7.50-7.41 (m, 3H), 3.91 (s, 3H), 2.59 (s, 3H), 2.47 (t, J=7.14 Hz, 2H), 1.63 (p, J=7.22 Hz, 2H), 1.5-1.29 (m, 4H), 0.91 (t, J=7.13 Hz, 3H); LCMS m/z: 244.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08487109B2 |
| 출처 데이터셋 | uspto-grants-2013_07 |
| ORD ID | ord-8fbef307a7ba4b17a36814314514ec12 |
| 출처 메모 | uspto-grants-2013_07 |