Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Ethynylcyclohexene → 1-(4-Cyclohex-1-enylethynyl-3-methoxy-phenyl)ethanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Ethynylcyclohexene | HCID 79128 | — |
| 반응물 | Toluene-4-sulfonic acid 4-acetyl-2-methoxy-phenyl ester | HCID 29800848 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 1-(4-Cyclohex-1-enylethynyl-3-methoxy-phenyl)ethanone | HCID 25221607 | — |
반응 단계
This product was prepared from toluene-4-sulfonic acid 4-acetyl-2-methoxy-phenyl ester and 1-ethynyl-cyclohexene following the general procedure for the Sonogashira cross-coupling process described above. Chromatography eluent: DCM; yield (114 mg, 90%); 1H NMR δ (CDCl3): 7.53-7.41 (m, 3H), 6.29 (m, 1H), 3.92 (s, 3H), 2.51 (s, 3H), 2.31-2.12 (dm, 4H), 1.73-1.57 (m, 4H); LCMS m/z: 254.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08487109B2 |
| 출처 데이터셋 | uspto-grants-2013_07 |
| ORD ID | ord-dc315de689f544b883d3cae1f9f48485 |
| 출처 메모 | uspto-grants-2013_07 |