Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 3-(2,5-dimethyl-1H-pyrrol-1-yl)-1-methyl-1H-pyrazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | 2,5-Hexanedione | HCID 8035 | — |
| 반응물 | 1-Methyl-3-aminopyrazole | HCID 137254 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 3-(2,5-dimethyl-1H-pyrrol-1-yl)-1-methyl-1H-pyrazole | HCID 13248995 | — |
반응 단계
To a solution of 1-methyl-1H-pyrazol-3-amine (9.5 g, 98 mmol) and acetonylacetone (11.2 g, 98 mmol) in toluene (150 mL), AcOH (1.5 mL) is added, heated to reflux with a water separator until the formation of water ceased. Concentrated to dry. The residue is purified by flash column to give product.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08541432B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-0937fb3db8924a38996162cfa19c76bf |
| 출처 메모 | uspto-grants-2013_09 |