Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanol → Tyrosine Methyl Ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | L-Tyrosine | HCID 6057 | — |
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 생성물 | Tyrosine Methyl Ester | HCID 70652 | 100% |
반응 단계
To a solution of L-tyrosine (45.3 g, 0.25 mol) in CH3OH (680 mL), SOCl2 (44.6 g, 0.375 mol) was added dropwise at 0° C. After addition, the mixture was allowed to warm to rt and then refluxed for overnight. The reaction mixture was concentrated to give L-tyrosine methyl ester (49.2 g, 100%), which was used in the next step without purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08487108B2 |
| 출처 데이터셋 | uspto-grants-2013_07 |
| ORD ID | ord-81cf74bb249a4b16970c0fb28ecabe21 |
| 출처 메모 | uspto-grants-2013_07 |