(S)-prop-1-en-2-yl 5,5-dimethyl-1-(N-methyl-N-(2-trimethylsilylethoxycarbonyl)amino)hexan-2-ylcarbamate → methyl 2-((R)-(3-chlorophenyl)((R)-1-((S)-5,5-dimethyl-1-(N-methyl-N-(2-trimethylsilylethoxycarbonyl)amino)hexan-2-ylcarbamoyl)piperidin-3-yl)methoxy)ethylcarbamate

반응식

[CH3:1][C:2]([CH3:26])([CH3:25])[CH2:3][CH2:4][C@H:5]([NH:18][C:19](=[O:24])OC(C)=C)[CH2:6][N:7]([CH3:17])[C:8]([O:10][CH2:11][CH2:12][Si:13]([CH3:16])([CH3:15])[CH3:14])=[O:9].[Cl:27][C:28]1[CH:29]=[C:30]([C@@H:34]([C@@H:43]2[CH2:48][CH2:47][CH2:46][NH:45][CH2:44]2)[O:35][CH2:36][CH2:37][NH:38][C:39](=[O:42])[O:40][CH3:41])[CH:31]=[CH:32][CH:33]=1>C1COCC1>[Cl:27][C:28]1[CH:29]=[C:30]([C@@H:34]([C@@H:43]2[CH2:48][CH2:47][CH2:46][N:45]([C:19](=[O:24])[NH:18][C@@H:5]([CH2:4][CH2:3][C:2]([CH3:1])([CH3:25])[CH3:26])[CH2:6][N:7]([CH3:17])[C:8]([O:10][CH2:11][CH2:12][Si:13]([CH3:14])([CH3:15])[CH3:16])=[O:9])[CH2:44]2)[O:35][CH2:36][CH2:37][NH:38][C:39](=[O:42])[O:40][CH3:41])[CH:31]=[CH:32][CH:33]=1