3-(3-Trifluoromethylphenyl)propanoic acid → HCID 86640027, 화합물

HRID 452617

반응식

HRID 452617 반응식
[F:1][C:2]([F:15])([F:14])[C:3]1[CH:4]=[C:5]([CH2:9][CH2:10][C:11]([OH:13])=O)[CH:6]=[CH:7][CH:8]=1.[C:16]([O:20][C:21](=[O:33])[NH:22][C:23]1[CH:28]=[C:27]([C:29]([NH:31][NH2:32])=[O:30])[CH:26]=[CH:25][N:24]=1)([CH3:19])([CH3:18])[CH3:17]>>[C:16]([O:20][C:21](=[O:33])[NH:22][C:23]1[CH:28]=[C:27]([C:29]([NH:31][NH:32][C:11](=[O:13])[CH2:10][CH2:9][C:5]2[CH:6]=[CH:7][CH:8]=[C:3]([C:2]([F:1])([F:15])[F:14])[CH:4]=2)=[O:30])[CH:26]=[CH:25][N:24]=1)([CH3:19])([CH3:17])[CH3:18]

참가 물질

3

반응물 2

HCID 27776833-(3-Trifluoromethylphenyl)propanoic acidHCID 86640026Tert-butyl [4-(hydrazinocarbonyl)-2-pyridyl]carbamate

생성물 1

HCID 86640027HCID 86640027, 화합물수율 80%

실험 절차

In the same manner as in Reference Example 1 and using 3-[3-(trifluoromethyl)phenyl]propionic acid instead of benzothiazole-6-carboxylic acid and tert-butyl[4-(hydrazinocarbonyl)-2-pyridyl]carbamate instead of tert-butyl carbazate, the title compound (yield 80%) was obtained as colorless crystals.

출처 및 근거

ORD 기록
ord-3927654647ac4fac96c829dcd3f6e2cb
출처 데이터셋
uspto-grants-2013_07
특허 번호
US08492378B2

연결된 노트

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