Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetoxyacetyl chloride → 2-Oxo-2-[2-[[3-[3-(trifluoromethoxy)phenyl]-1-benzofuran-5-yl]carbonyl]hydrazino]ethyl acetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetoxyacetyl chloride | HCID 26297 | — |
| 반응물 | 3-[3-(Trifluoromethoxy)phenyl]-1-benzofuran-5-carbohydrazide | HCID 68664388 | — |
| 생성물 | 2-Oxo-2-[2-[[3-[3-(trifluoromethoxy)phenyl]-1-benzofuran-5-yl]carbonyl]hydrazino]ethyl acetate | HCID 68663979 | 94% |
반응 단계
In the same manner as in Reference Example 61 and using 3-[3-(trifluoromethoxy)phenyl]-1-benzofuran-5-carbohydrazide instead of ethyl 2-aminoisonicotinate and acetoxyacetyl chloride instead of 3-phenylpropanoyl chloride, the title compound (yield 94%) was obtained as colorless crystals.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08492378B2 |
| 출처 데이터셋 | uspto-grants-2013_07 |
| ORD ID | ord-b8ee4722838a4af8a11e55105d686a9e |
| 출처 메모 | uspto-grants-2013_07 |