Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Acetoxyisobutyroyl chloride → 2-[2-[[3-(2,5-Difluorophenyl)-1-benzofuran-5-yl]carbonyl]hydrazino]-1,1-dimethyl-2-oxoethyl acetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Acetoxyisobutyroyl chloride | HCID 123496 | — |
| 반응물 | 3-(2,5-Difluorophenyl)-1-benzofuran-5-carbohydrazide | HCID 68664374 | — |
| 생성물 | 2-[2-[[3-(2,5-Difluorophenyl)-1-benzofuran-5-yl]carbonyl]hydrazino]-1,1-dimethyl-2-oxoethyl acetate | HCID 68663113 | 85% |
반응 단계
In the same manner as in Reference Example 129 and using 3-(2,5-difluorophenyl)-1-benzofuran-5-carbohydrazide instead of 3-bromo-1-benzofuran-5-carbohydrazide and 2-chloro-1,1-dimethyl-2-oxoethyl acetate instead of (1S)-2-chloro-1-methyl-2-oxoethyl acetate, the title compound (yield 85%) was obtained as colorless crystals.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08492378B2 |
| 출처 데이터셋 | uspto-grants-2013_07 |
| ORD ID | ord-33743152b32443c492c7f9c3145b33ee |
| 출처 메모 | uspto-grants-2013_07 |