3-(3-Fluorophenyl)propionic acid → HCID 68663623, 화합물

HRID 452746

반응식

HRID 452746 반응식
[CH3:1][N:2]1[C:6]2[CH:7]=[C:8]([C:11]([NH:13][NH2:14])=[O:12])[CH:9]=[CH:10][C:5]=2[N:4]=[CH:3]1.[F:15][C:16]1[CH:17]=[C:18]([CH2:22][CH2:23][C:24](O)=O)[CH:19]=[CH:20][CH:21]=1>>[F:15][C:16]1[CH:17]=[C:18]([CH2:22][CH2:23][C:24]2[O:12][C:11]([C:8]3[CH:9]=[CH:10][C:5]4[N:4]=[CH:3][N:2]([CH3:1])[C:6]=4[CH:7]=3)=[N:13][N:14]=2)[CH:19]=[CH:20][CH:21]=1

참가 물질

3

반응물 2

HCID 27374893-(3-Fluorophenyl)propionic acidHCID 68663278HCID 68663278, 화합물

생성물 1

HCID 68663623HCID 68663623, 화합물수율 66%

실험 절차

In the same manner as in Example 14 and using 1-methyl-1H-benzimidazole-6-carbohydrazide instead of 1H-benzotriazole-5-carbohydrazide and 3-(3-fluorophenyl)propionic acid instead of 3-(3-cyanophenyl)propionic acid, the title compound (yield 66%) was obtained as colorless crystals.

출처 및 근거

ORD 기록
ord-fb5196244c7a4e2fb661e640b262ec2e
출처 데이터셋
uspto-grants-2013_07
특허 번호
US08492378B2

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