Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Fluorobenzyl bromide → 2-[(3-Fluorobenzyl)thio]-5-[3-[4-(methylsulfinyl)phenyl]-1-benzofuran-5-yl]-1,3,4-oxadiazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Fluorobenzyl bromide | HCID 68007 | — |
| 반응물 | HCID 178504596 | HCID 178504596 | — |
| 생성물 | 2-[(3-Fluorobenzyl)thio]-5-[3-[4-(methylsulfinyl)phenyl]-1-benzofuran-5-yl]-1,3,4-oxadiazole | HCID 68663363 | 87% |
반응 단계
In the same manner as in Example 7 and using 5-[3-[4-(methylsulfinyl)phenyl]-1-benzofuran-5-yl]-1,3,4-oxadiazole-2-thiol instead of 5-(1H-indazol-5-yl)-1,3,4-oxadiazole-2-thiol and 3-fluorobenzyl bromide instead of 3-(trifluoromethyl)benzyl chloride, the title compound (yield 87%) was obtained as colorless crystals.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08492378B2 |
| 출처 데이터셋 | uspto-grants-2013_07 |
| ORD ID | ord-0c8b8bcbbb254e52b8b751ad2659e22a |
| 출처 메모 | uspto-grants-2013_07 |