Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrazine hydrate (1:1) → 3-[3-(Trifluoromethoxy)phenyl]-1-benzofuran-5-carbohydrazide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrazine hydrate (1:1) | HCID 24654 | — |
| 반응물 | Methyl 3-[3-(trifluoromethoxy)phenyl]-1-benzofuran-5-carboxylate | HCID 68664542 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 3-[3-(Trifluoromethoxy)phenyl]-1-benzofuran-5-carbohydrazide | HCID 68664388 | — |
반응 단계
A solution of methyl 3-[3-(trifluoromethoxy)phenyl]-1-benzofuran-5-carboxylate (6.80 g, 20.2 mmol) and hydrazine monohydrate (9.92 mL, 202.2 mmol) in ethanol (70 mL) was heated under reflux overnight. After cooling, the precipitate was collected by filtration to give 3-[3-(trifluoromethoxy)phenyl]-1-benzofuran-5-carbohydrazide.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08492378B2 |
| 출처 데이터셋 | uspto-grants-2013_07 |
| ORD ID | ord-56e45ac22a3f4ebeb9cfd5ed9852e527 |
| 출처 메모 | uspto-grants-2013_07 |