Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Metformin Hydrochloride → HCID 178476642, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Metformin Hydrochloride | HCID 14219 | — |
| 반응물 | Sodium Acetate Trihydrate | HCID 23665404 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | HCID 178476642 | HCID 178476642 | 51.6% |
반응 단계
20.0 g (1 equivalent) of metformin hydrochloride, 50 Ml of water, and 19.72 g (1.2 equivalents) of sodium acetate trihydrate were added to a reactor, and stirred. Then the resulting crystal was filtered and washed with acetone, and then dried at 60° C. to obtain 11.72 g of metformin acetate (yield: 51.3%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08541474B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-8f6f02ec54e8446e91f4b5525381d122 |
| 출처 메모 | uspto-grants-2013_09 |