Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetic Acid → HCID 178476642, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetic Acid | HCID 176 | — |
| 반응물 | Isopropanol | HCID 3776 | — |
| 반응물 | HCID 178484382 | HCID 178484382 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | HCID 178476642 | HCID 178476642 | 47.8% |
반응 단계
78 g (1 equivalent) of metformin free base, 234 Ml of isopropanol, 234 Ml of water and 57 Ml (1.65 equivalents) of acetic acid were added to a reactor, and stirred. The resulting crystal was filtered and washed with isopropanol, and then dried at 60° C. to obtain 54.6 g of metformin acetate (yield: 47.8%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08541474B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-cd5a98c6f5d745438361e4b8efe6e631 |
| 출처 메모 | uspto-grants-2013_09 |