2-(4-Chloro-butyl)-2H-[1,2,4]triazine-3,5-dione → HCID 67512578, 화합물
반응식
[Cl:1][CH2:2][CH2:3][CH2:4][CH2:5][N:6]1[C:11](=[O:12])[NH:10][C:9](=[O:13])[CH:8]=[N:7]1.[C:14]([C:18]1[N:23]=[C:22]([N:24]2[CH2:29][CH2:28][NH:27][CH2:26][CH2:25]2)[CH:21]=[C:20]([CH:30]([F:32])[F:31])[N:19]=1)([CH3:17])([CH3:16])[CH3:15]>CN1CCCC1>[ClH:1].[C:14]([C:18]1[N:23]=[C:22]([N:24]2[CH2:29][CH2:28][N:27]([CH2:2][CH2:3][CH2:4][CH2:5][N:6]3[C:11](=[O:12])[NH:10][C:9](=[O:13])[CH:8]=[N:7]3)[CH2:26][CH2:25]2)[CH:21]=[C:20]([CH:30]([F:31])[F:32])[N:19]=1)([CH3:17])([CH3:15])[CH3:16]참가 물질
4
실험 절차
2-{4-[4-(2-tert-Butyl-6-difluoromethyl-pyrimidin-4-yl)-piperazin-1-yl]butyl}-2H-[1,2,4]triazine-3,5-dione hydrochloride was prepared from 2-(4-chloro-butyl)-2H-[1,2,4]triazine-3,5-dione and 2-tert-butyl-4-piperazin-1-yl-6-difluoromethyl-pyrimidine by analogy to the process described in example 1 using N-methyl-pyrrolidine as solvent.