1,2-Dibromoethane → 2,3-dihydro-2,2-dimethyl-7-(2-bromoethoxy)-4H-1,3-benzoxazin-4-one

HRID 4539

반응식

HRID 4539 반응식
[CH3:1][C:2]1([CH3:14])[NH:7][C:6](=[O:8])[C:5]2[CH:9]=[CH:10][C:11]([OH:13])=[CH:12][C:4]=2[O:3]1.[Br:15][CH2:16][CH2:17]Br>C(O)(C)C>[CH3:1][C:2]1([CH3:14])[NH:7][C:6](=[O:8])[C:5]2[CH:9]=[CH:10][C:11]([O:13][CH2:17][CH2:16][Br:15])=[CH:12][C:4]=2[O:3]1

참가 물질

4

반응물 2

HCID 78391,2-DibromoethaneHCID 137544122,3-dihydro-2,2-dimethyl-7-hydroxy-4H-1,3-benzoxazin-4-one

생성물 1

HCID 137544152,3-dihydro-2,2-dimethyl-7-(2-bromoethoxy)-4H-1,3-benzoxazin-4-one

시약·촉매·용매 1

HCID 3776Isopropanol용매

실험 절차

16.2 g of 2,3-dihydro-2,2-dimethyl-7-hydroxy-4H-1,3-benzoxazin-4-one are reacted analogously to Example (3a) with 84 ml of 1,2-dibromoethane and yield 2,3-dihydro-2,2-dimethyl-7-(2-bromoethoxy)-4H-1,3-benzoxazin-4-one having a melting point of 156°-158° (from isopropanol).

출처 및 근거

ORD 기록
ord-1b52e7de41e1401c8a5258398141f605
출처 데이터셋
uspto-grants-1988_02
특허 번호
US04727067

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