Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Epichlorohydrin → 4-(2,3-Epoxypropoxy)salicylic acid methyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Epichlorohydrin | HCID 7835 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | Methyl 2,4-Dihydroxybenzoate | HCID 16523 | — |
| 생성물 | 4-(2,3-Epoxypropoxy)salicylic acid methyl ester | HCID 12611335 | — |
반응 단계
By refluxing 34 g of 2,4-dihydroxybenzoic acid methyl ester with 185 g of epichlorohydrin and 35 g of potassium carbonate for 2 to 3 hours, and chromatographing the crude product on 100 g of silica gel (elution with toluene), 4-(2,3-epoxypropoxy)salicylic acid methyl ester having a melting point of 53°-55° is obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04727067 |
| 출처 데이터셋 | uspto-grants-1988_02 |
| ORD ID | ord-04f489d6f4b84e0caced2494d503c25d |
| 출처 메모 | uspto-grants-1988_02 |