Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methylhydrazine → 2-(4-Chlorophenyl)-3-((6-(2-methylhydrazinyl)pyrazin-2-yl)methyl)imidazo[1,2-a]pyridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methylhydrazine | HCID 6061 | — |
| 반응물 | 1-(2-((6-Chloro-2-phenylimidazo[1,2-a]pyridin-3-yl)methylamino)pyrimidin-4-yl)-4-methylpiperidin-4-ol | HCID 67029099 | — |
| 반응물 | 2-(4-Chlorophenyl)-3-((6-chloropyrazin-2-yl)methyl)imidazo[1,2-a]pyridine | HCID 86655124 | — |
| 생성물 | 2-(4-Chlorophenyl)-3-((6-(2-methylhydrazinyl)pyrazin-2-yl)methyl)imidazo[1,2-a]pyridine | HCID 67027557 | — |
반응 단계
The title compound was prepared according to the experimental for compound 187 from 2-(4-chlorophenyl)-3-((6-chloropyrazin-2-yl)methyl)imidazo[1,2-a]pyridine and methylhydrazine. M/e+ 365 for C19H18ClN6 (M+H)+; 1H-NMR (400 MHz, CDCl3) δ 8.41 (s, 1H), 8.12 (d, J=6.9 Hz, 1H), 7.83 (d, J=8.4 Hz, 2H), 7.73 (s, 1H), 7.63 (d, J=9.1 Hz, 1H), 7.41 (d, J=8.4 Hz, 2H), 7.19 (m, 1H), 6.78 (t, J=6.9 Hz, 1H), 4.36 (s, 2H), 3.88 (bs, 2H), 3.18 (s, 3H) ppm.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08497278B2 |
| 출처 데이터셋 | uspto-grants-2013_07 |
| ORD ID | ord-83efa8abc54a46d8ab4a2e508b40d52b |
| 출처 메모 | uspto-grants-2013_07 |