4-Toluenesulfonyl chloride → 2,2-Difluoro-2-pyridin-2-ylethyl 4-methylbenzenesulfonate

HRID 45568

반응식

HRID 45568 반응식
[F:1][C:2]([F:11])([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][N:6]=1)[CH2:3][OH:4].[C:12]1([CH3:22])[CH:17]=[CH:16][C:15]([S:18](Cl)(=[O:20])=[O:19])=[CH:14][CH:13]=1>>[CH3:22][C:12]1[CH:17]=[CH:16][C:15]([S:18]([O:4][CH2:3][C:2]([F:1])([F:11])[C:5]2[CH:10]=[CH:9][CH:8]=[CH:7][N:6]=2)(=[O:20])=[O:19])=[CH:14][CH:13]=1

참가 물질

3

반응물 2

HCID 73974-Toluenesulfonyl chlorideHCID 99422162,2-Difluoro-2-(pyridin-2-YL)ethanol

생성물 1

HCID 582496422,2-Difluoro-2-pyridin-2-ylethyl 4-methylbenzenesulfonate

실험 절차

reacting 2,2-difluoro-2-pyridin-2-ylethanol with 4-toluenesulfonyl chloride to form 2,2-difluoro-2-pyridin-2-ylethyl 4-methylbenzenesulfonate, which is converted to compound of formula (K2); and

출처 및 근거

ORD 기록
ord-1f8c84fff2814dc9b905798423f88e43
출처 데이터셋
uspto-grants-2013_09
특허 번호
US08541580B2

연결된 노트

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