참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Potassium Hydroxide | HCID 14797 | — |
| 반응물 | 1-(4-Bromophenyl)Cyclopropanecarbonitrile | HCID 2795273 | — |
| 용매 | Ethylene Glycol | HCID 174 | — |
| 생성물 | 1-(4-Bromophenyl)cyclopropane-1-carboxylic acid | HCID 16227966 | — |
반응 단계
1-(4-Bromo-phenyl)-cyclopropanecarbonitrile (5 g, 22.5 mmol) and potassium hydroxide (5 g, 89.3 mmol) were combined in ethylene glycol (70 mL), and the reaction was stirred at 180° C. for 4 hours. The mixture was poured into H2O, acidified, and filtered to give the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08541587B2 |
|---|
| 출처 데이터셋 | uspto-grants-2013_09 |
|---|
| ORD ID | ord-98ecc165e9fa444bb6cf22925aea77b3 |
|---|
| 출처 메모 | uspto-grants-2013_09 |
|---|
