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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 456023생성일: 2026년 10월 25일

4'-Chloro-4-biphenylol → 2-[(4-{[(4'-Chlorobiphenyl-4-yl)oxy]acetyl}-1,3-thiazol-2-yl)thio]-2-methylpropionic acid tert-butyl ester

https://huagongshe.com/reaction/456023

반응식

참여 물질

역할이름HCID투입량
반응물4'-Chloro-4-biphenylolHCID 91589—
반응물HCID 58451403HCID 58451403—
생성물2-[(4-{[(4'-Chlorobiphenyl-4-yl)oxy]acetyl}-1,3-thiazol-2-yl)thio]-2-methylpropionic acid tert-butyl esterHCID 6739224917.1%

반응 단계

By an operation similar to that in Example 2-1 and using 2-{[4-(chloroacetyl)-1,3-thiazol-2-yl]thio}-2-methylpropionic acid tert-butyl ester (561 mg) obtained in Example 1 and 4′-chlorobiphenyl-4-ol (307 mg), 2-[(4-{[(4′-chlorobiphenyl-4-yl)oxy]acetyl}-1,3-thiazol-2-yl)thio]-2-methylpropionic acid tert-butyl ester (129 mg) was obtained. Furthermore, by operations similar to those in Example 2-2 and 2-3, the title compound (36 mg) was obtained.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08497382B2
출처 데이터셋uspto-grants-2013_07
ORD IDord-69fa158aac1f4098a89e987794ae1037
출처 메모uspto-grants-2013_07