Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4'-Chloro-4-biphenylol → 2-[(4-{[(4'-Chlorobiphenyl-4-yl)oxy]acetyl}-1,3-thiazol-2-yl)thio]-2-methylpropionic acid tert-butyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4'-Chloro-4-biphenylol | HCID 91589 | — |
| 반응물 | HCID 58451403 | HCID 58451403 | — |
| 생성물 | 2-[(4-{[(4'-Chlorobiphenyl-4-yl)oxy]acetyl}-1,3-thiazol-2-yl)thio]-2-methylpropionic acid tert-butyl ester | HCID 67392249 | 17.1% |
반응 단계
By an operation similar to that in Example 2-1 and using 2-{[4-(chloroacetyl)-1,3-thiazol-2-yl]thio}-2-methylpropionic acid tert-butyl ester (561 mg) obtained in Example 1 and 4′-chlorobiphenyl-4-ol (307 mg), 2-[(4-{[(4′-chlorobiphenyl-4-yl)oxy]acetyl}-1,3-thiazol-2-yl)thio]-2-methylpropionic acid tert-butyl ester (129 mg) was obtained. Furthermore, by operations similar to those in Example 2-2 and 2-3, the title compound (36 mg) was obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08497382B2 |
| 출처 데이터셋 | uspto-grants-2013_07 |
| ORD ID | ord-69fa158aac1f4098a89e987794ae1037 |
| 출처 메모 | uspto-grants-2013_07 |