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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 456200생성일: 2026년 10월 25일

Methyl 2-(4-methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)phenyl)acetate → [4'-Fluoro-6-methoxy-2'-((4S,5R)-4-methyl-2-oxo-5-phenyl-oxazolidin-3-ylmethyl)-biphenyl-3-yl]-acetic acid methyl ester

https://huagongshe.com/reaction/456200

반응식

참여 물질

역할이름HCID투입량
반응물Methyl 2-(4-methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)phenyl)acetateHCID 57576289—
반응물(4S,5R)-3-(2-Bromo-5-fluoro-benzyl)-4-methyl-5-phenyl-oxazolidin-2-oneHCID 58120056—
생성물[4'-Fluoro-6-methoxy-2'-((4S,5R)-4-methyl-2-oxo-5-phenyl-oxazolidin-3-ylmethyl)-biphenyl-3-yl]-acetic acid methyl esterHCID 58120044—

반응 단계

Prepared according to the procedure described in Example 1, Step 4, using the following starting materials: (4S,5R)-3-(2-bromo-5-fluoro-benzyl)-4-methyl-5-phenyl-oxazolidin-2-one and [4-methoxy-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-acetic acid methyl ester.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08497381B2
출처 데이터셋uspto-grants-2013_07
ORD IDord-607fd1383d994e33897cd11ff92f6378
출처 메모uspto-grants-2013_07