Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium borohydride → 9-cis-Retinol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium borohydride | HCID 4311764 | — |
| 반응물 | 9-Cis-Retinal | HCID 6436082 | — |
| 반응물 | (2Z,6E,8E)-3,5,7-trimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,6,8-trien-1-ol | HCID 57390897 | — |
| 생성물 | 9-cis-Retinol | HCID 9947823 | — |
반응 단계
All-trans-retinol was obtained as a gift from Dr. Christian Eckhoff of Hoffmann-LaRoche, Inc. (Nutley, N.J.), and 13-cis-retinol was purchased from Sigma. 9-cis-Retinol was synthesized by NaBH4 reduction of authentic 9-cis-retinaldehyde (Sigma) and subsequently purified by normal phase HPLC essentially as we have described for 11-cis-retinol synthesis and purification (25). All-trans-, 13-cis-, and 9-cis-retinaldehydes were purchased from Sigma.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07186534B1 |
| 출처 데이터셋 | uspto-grants-2007_03 |
| ORD ID | ord-fed8c9324be34a5a8e6c9e26c2754501 |
| 출처 메모 | uspto-grants-2007_03 |