351458-51-0 → 351456-35-4

HRID 456647노트

반응식

HRID 456647 반응식
[N+:1]([C:4]1[CH:5]=[C:6]2[C:10](=[CH:11][CH:12]=1)[NH:9][N:8]=[C:7]2[C:13]1[NH:14][CH:15]=[CH:16][CH:17]=1)([O-])=O>C(O)C.[Pd]>[NH:14]1[CH:15]=[CH:16][CH:17]=[C:13]1[C:7]1[C:6]2[C:10](=[CH:11][CH:12]=[C:4]([NH2:1])[CH:5]=2)[NH:9][N:8]=1

참가 물질

4

반응물 1

HCID 135409235351458-51-0

생성물 1

HCID 135506487351456-35-4수율 62.2%

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 702Ethanol용매

실험 절차

5-Nitro-3-(1H-pyrrol-2-yl)-1H-indazole (37 mg) (from Example 22) was hydrogenated using 5% Pd/C (20 mg) in ethanol (5 mL) for 2 hours. The reaction was filtered and the filtrate was concentrated to give 20 mg of the titled compound.

후처리

  1. customfor 2 hours
  2. filtrationThe reaction was filtered
  3. concentrationthe filtrate was concentrated

출처 및 근거

ORD 기록
ord-87046f4411624b4d98d508f153afedcb
출처 데이터셋
uspto-grants-2007_03
특허 번호
US07186716B2

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