Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Allyl bromide → Methyl 2-(allyloxy)-4-methoxybenzoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Allyl bromide | HCID 7841 | — |
| 반응물 | Cesium carbonate | HCID 10796 | — |
| 반응물 | Methyl 4-methoxysalicylate | HCID 79523 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | Methyl 2-(allyloxy)-4-methoxybenzoate | HCID 10242646 | — |
반응 단계
To a solution of methyl 4-methoxysalicylate (2.0 g, 11 mmol) in DMP (20 mL) at room temperature was added Cs2CO3 (1.3 eq, 4.7 g) and allyl bromide (1.3 eq, 1.23 mL). After 2 hr, reaction mixture was diluted with EtOAc and washed with water (3×), brine (1×). The organic layer was dried over Na2SO4 and concentrated to provide the product as a pale yellow oil. Product was used without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07186746B2 |
| 출처 데이터셋 | uspto-grants-2007_03 |
| ORD ID | ord-78a6b749accd43fcb538a702fbbb6bdf |
| 출처 메모 | uspto-grants-2007_03 |